Job Search Results

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

External / Field Activities:
1. Scientific Exchange with Thought Leaders
Proactively and/or reactively interact with healthcare providers, as appropriate, through face-to-face meetings and other available means of communication, by focusing on activities described in Medical plans, in alignment with the customer-centric model and overall therapeutic area/brand strategies.

Develop and maintain contacts with Thought Leaders, in accordance with the strategy to further understand and gain both insight and/or input into treatment patterns, unmet medical needs, patient needs and behaviors.

Ensure appropriate response to unsolicited scientific questions or requests posed by Health Care Providers for approved products (in and off label), and for products in development.

Contribute to involvement of Thought Leaders, as required and as appropriate, in BMSsponsored studies and other scientific activities.

2. Collect and communicate Field Medical Insights (FMI)
Profiling of medical landscape within the Disease Area and continuously update this knowledge, including expertise in products, patient treatment trends, unmet medical needs, clinical trials and scientific activities.

Ensure awareness of current Key Insight Topics and Questions and proactively contribute insights gained from healthcare provider interactions to relevant internal stakeholders.

3. Provide Medical Services to External Customers
Liaise appropriately and effectively with the Medical Information department to develop a systematic follow up interaction plan with Health Care Providers to ensure customer satisfaction with the information received in response to their unsolicited scientific questions or requests; and is prepared to discuss these responses and/or expand on the content upon the HCP’s request.

Exhibit a high degree of familiarity with, and proficiency in, centrally developed scientific resources and presentations. Present information to HCPs, as appropriate, ensuring medical accuracy and compliance with local procedures/regulation, ethical, and legal guidelines.

Identify appropriate candidates for the local speaker bureau

Key facilitator during formal Speaker Training meetings, and/or through regular one-to-one education, ensuring speakers are skilled on the latest approved resources.

4. Provide clinical trial support, Clinical Trial/Survey Identification, Planning and Execution

Lead the identification, at an early stage, of potential opportunities for country
participation in clinical development programs. Lead early mapping of centers of excellence, treatment trends and recruitment potential in untapped therapeutic areas / with new compounds.

Contribute to the ‘early prioritization’ of development programs for the country by integrating data on disease incidence / prevalence, treatment patterns, unmet medical needs and interest from the scientific community.

Participate actively in providing input to the RCO Hub on trial and survey feasibility and site suitability, based on knowledge of the field and through direct contacts with potential investigators.

Facilitate clinical trial activities between BMS and investigators for both BMS sponsored(interventional and non-interventional) and Investigator sponsored trials).

Provides support to the Clinical Site Manager, as requested and as per Scope
document, for site support activities relating to the conduct of a BMS sponsored clinical trial.

Internal / Medical Strategy Activities:
1. Country Medical Strategy Key Contributors
Generate and execute the Local Medical Plan, and contribute to the development of integrated Local Brand Plans and strategies with reference to recent publications around patient’s needs and treatment trends, and as derived from contacts with Thought Leaders
and other HCPs or payers.

Identify the need for Consultants and/or Advisory Boards and execute
engagements according to strategy.

Contribute to the development of scientific publications or presentations, as appropriate.

Lead development and execution of educational Programs and Symposia and ensure flawless execution of such activities, where permitted.

2. Medical support for internal stakeholders
As appropriate, contribute to the initial and ongoing medical/scientific disease area and product-specific training of internal and field-based BMS personnel (Brand team, Sales force, Clinical Operation, etc), enabling understanding and balanced communication of the scientific benefits and clinical values of brands.

Provide scientific support to Internal Stakeholders, specifically but not limited to Marketing, Regulatory, HEOR, Pharmacovigilance, Legal Counsel and Market Access.

Contribute to the execution of Medical Education activities by reviewing the proposed presentations for scientific rigor and accuracy, where Company policies, and applicable laws, regulations and ethical standards permit it.

Promotional Material Contributor & Reviewer
Contribute to the development of clinical data to be included in promotional materials and review the overall material.

3. Compliance
􀁸 Endorse and implement a culture of compliance
􀁸 Develop an understanding and competence of SOPs, GCP and ICH, as well as legal and ethical standards
􀁸 Immediately alert management or the Compliance Department to any possible compliance issues

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

BMS Hyderabad is an integrated global hub where our work is focused on helping patients prevail over serious diseases by building sustainable and innovative solutions. This important science, technology, and innovation center will support a range of technology and drug development activities that will help us usher in the next wave of innovation.
Functional Area Description

Global Trial Managers, crossing all therapeutic areas and research phases, collaborate with cross-functional teams to drive operational aspects of complex, global clinical research studies from concept to final clinical study report. Position Summary / Objective

• Provides strategic and operational leadership of clinical research studies to ensure delivery on time, within budget, and of high quality in compliance with ICH/GCP, Regulatory Authorities' regulations/guidelines, and applicable SOPs/WPs.

• Independently leads complex, large, global in-house or outsourced, NonRegistrational Data Generating or Registrational Data Generating trials/studies at any point in the life cycle of the trial/study (i.e. start up, maintenance, or close-out).

• Acts as the primary operational contact for the study and leads the crossfunctional global team for execution of the study. • May provide operational leadership of one or more cross-functional Study Team(s) and/or performance and quality oversight of one or more Contract Research Organization (CRO) teams and vendors.

• Has high global organizational impact and influence, and significant impact on function and Study Team.

Position Responsibilities

Responsibilities involve a combination of execution and oversight, dependent on the sourcing model, to ensure deliverables and may include, but are not limited to, the following:

Project Management

• Directs and delegates to the assigned Global Trial Management Staff as applicable

• Drives study execution utilizing available performance metrics and quality indicators and study milestones and drivers

• Oversees clinical monitoring quality and adherence to established processes and plans.

• Develops, manages, and maintains study deliverables (i.e. timelines, study plans, etc.) through collaboration with internal and external stakeholders using data and strong interpersonal influencing skills to make robust data driven decisions.

• Proactively identifies potential risks and develops/implements actions to avoid/mitigate and make the appropriate trade-offs of balancing risks with study deliverables and costs.

Job Description

• Maintains/updates data as appropriate in project management tools including CTMS.

• Troubleshoots complex issues with little guidance and support.

• Informs operational program lead(s) and other leadership (as appropriate) on overall clinical trial plans, recruitment status, and raises potential issues/mitigation.

• Leads, develops, and implements cross-functional/global initiatives and best practices.

• Creates, maintains, and implements project management tools at the study level (e.g. actions, decisions, issues log and risk management plan). Study Planning and Conduct

• Supports and oversees country and site feasibility/selection processes with use of robust data.

• Provides operational and strategic input into Study Team and study documents.

• Collaborates with CSO on global investigational product [IP] supply forecasting/management.

• Participates in the subject recruitment/retention strategy and related initiatives (e.g. recruitment material).

• Participates in clinical service provider (vendor) selection, specification development, and management/oversight.

• Oversees TMF set-up, ongoing quality review, operational oversight memo, and requests final reconciliation.

• Provides input to and reviews study training for Study Team, investigational sites, and vendors in collaboration with the Clinical Scientist. • Oversees study specific CSR appendices.

• Provides input and communicates with the appropriate teams for response to country/regulatory and IRB/IEC.

• Proactively manages issues and information sharing with key internal/external stakeholders with use of standardized reports and other mechanisms.

• Highly proactive risk identification, contingency planning, innovative problem solving, and the ability to solve multiple problems with varying degrees of complexity for multiple functions and understands when escalation is needed.

• Oversees service providers without supervision.

• Leads Audit Response Team and CAPA and participates in inspections.

• Supports the development/management/review vendor scope of work (SOW), invoices, and accruals as per the contract, quality requirements, and budget. Relationship Management

• Proactively develops and maintains collaborative relationships with internal partners/stakeholders across the multidisciplinary teams.

• Manages external partners including Contract Research Organizations (CROs), Academic Research Organizations (AROs), and other clinical service providers as applicable.

• Influences key stakeholders inside/outside of the team and capitalizes on established relationships.

Leadership Competencies

• Creates realistic plans that clearly define goals, milestones, responsibilities and results.

• Maintains focus on strategic objectives while accomplishing operational goals.

• Places a priority on getting results with an emphasis on high quality outcomes.

• Holds self and others accountable for accomplishing goals.

• Makes timely, data-driven decisions while balancing against daily priorities.

• Develops and maintains effective working relationships with people across cultures.

• Encourages collaboration across teams, functions, and geographies. • Ensures that conflict is handled constructively so that performance is not impacted.

• Displays a willingness to challenge the status quo and take risks.

• Responds resourcefully to changing business demands and opportunities, proactively looking for ways the team can contribute.

• Maintains optimism, support and composure in times of change, uncertainty, or stress.

• Executes/delivers on corporate objectives and drives goals. • Leads global cross functional therapeutic programs.

• Creates global solutions for processes.

• Acts as mentor, driver, and motivator to Global Trial Specialist, Associate GTMs, GTMs, and others in the Study Team and function, especially during challenging times.

• Frequently encourages others to consider new approaches and ideas, avoiding getting stuck in a "one right way" approach.

• Models and promotes positive team behaviors in a cross-functional setting by inspiring and holding others accountable for accomplishing goals, building a culture of energy and commitment that challenges people to excel, recognizing and rewarding accomplishments, managing issues, and providing guidance/feedback on performance.

• Can be viewed as a SME by cross functional teams. • May participate in company initiatives, leads continuous improvement initiatives, and shares knowledge where applicable. •

Provides guidance regarding company policies and procedures.

Degree Requirements

BA/BS or equivalent degree in relevant discipline

Experience Requirements

• Minimum 6 years of clinical study management experience of which at least 2 years should have been in direct multinational study management.

• Experience in leading global clinical trials and multi-functional teams.

• Demonstrated project management and organizational skills with strong presentation and communication abilities.

• Experience with electronic quality, compliance and CTMS systems.

• Risk management experience preferred.

• Experience in managing CROs experience is a plus. Key Competency Requirements

• Demonstrated project management and organizational skills with strong presentation and communication abilities.

• Ability to see and understand how work at hand may have program or global implications and follows through to connect appropriate stakeholders Version Technical Competencies

• Strategic clinical trial project management and study management expert. • Intermediate knowledge of clinical trial forecasting, and financial management. • Expert knowledge of ICH/GCP, regulatory guidelines/directives, and drug development and Clinical Trial Process (CTP).

• Expert level cross functional awareness. • Proven success in using oral/written communication skills to influence, inform, or guide others.

• Fosters a continuous learning mindset.

• Computer skills -

Microsoft applications including (but not limited to), Word, Excel, PowerPoint. • Proficiency in study tools including electronic system skills – e.g. CTMS / eTMF

Management Competencies

• Leadership/influence and negotiating management skills.

• Ability to effectively lead a cross-functional team in a matrix environment.

• Time management skills - ability to effectively multi-task and set priorities for self and assists others with the same.

• Has the command of the projects, the ability to zoom in and out as the situation demands and deliver high quality presentations to senior and executive leadership within and outside of BMS (as appropriate).

• Has critical thinking skills for problem solving and the lateral and strategic thinking capacity to drive the study(ies) and understanding the upstream, downstream and lateral implications of decisions that affect study outcomes and timelines.

• Proven problem-solving skills to address and overcome complex safety and compliance related issues during clinical program implementation and execution.

• Excellent negotiating and influencing skills.

• Adaptable and flexible—willing/able to adjust to multiple demands and shifting priorities and demonstrates ability to meet day-to-day challenges with confidence and professionalism.
#HYDDD #LI-Hybrid

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

主要职责 (岗位相关):
•    有深入的产品知识和疾病领域知识
•    达成/超越区域目标
•    执行市场经理阐明的市场战略。从恰当的细分市场里甄别出目标HCP并与之合作, 达成推广计划
•    充分了解所在地区和所负责区域的关键HCPs
•    更新客户数据
•    协调当地的“院内会议”
•    及时更新HCP的信息，根据计划进行拜访。
•    建立和维护和关键HCP的联系, 理解客户(医学)需求。
•    达成并保持公司关于拜访率、知识水平、能力、行为和个人形象方面的要求。
•    定期（每天）在ETMS 系统中报告拜访情况。
•    提供准确的报告，并且根据规定的流程联系直接主管。
•    提供给直接主管关于BMS 推广材料有效性的信息。.
•    通过参加培训、会议、和自学医学文献以发展和提高专业知识
•    和团队成员分享自己的知识和经验。
•    管理好专业设备和促销资料，确保完好。

岗位要求
•    具备医药，生命科学相关本科以上学历
•    熟悉当地医院的推广工作
•    1-3 年销售经验
•    有肿瘤经验者优先考虑
•    具备良好的人际沟通技巧，团队合作精神，能独立分析解决问题并在压力下工作。

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

When you join BMS, you are joining a diverse, high-achieving team united by a common mission. 

The Discovery Biotherapeutics team at BMS seeks to understand the structure and function of complex molecules such as bispecific antibodies, antibody drug conjugates and endogenous proteins in order to optimize their utility as therapeutic agents.  We collaborate with biology and translational scientists imbedded in the Thematic Research Centers in order to prosecute Targets and Biological pathways with disease modifying potential. By using a blend of internal and external technologies and capabilities, we work to discover and deliver first-in-class as well as best-in-class molecules that warrant clinical evaluation for patient benefit.

Here, you’ll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You’ll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.

Senior Scientist Biotherapeutics Developability

Bristol Myers Squibb is seeking a highly motivated and innovative Senior Scientist with demonstrated expertise in antibody developability and characterization of monoclonal antibodies, bi/multispecifics, Fc-fusion proteins, and antibody-drug conjugates (ADCs) to join our Discovery Biotherapeutics team. Responsibilities will include a range of activities related to antibody and therapeutic protein developability characterization including but not limited to high-throughput plate-based screening for polyreactivity, analytical chromatographic methods for hydrophobicity, molecule integrity and pharmacokinetic prediction, and high throughput assays for manufacturability. This role will work in close collaboration with the protein engineering and characterization teams to test, design and optimize early to late-stage therapeutics to accelerate biotherapeutic discovery. The ideal candidate should also have knowledge/experience in protein chemistry, protein engineering, in silico modeling and prediction, and generation of large high-quality datasets to aid in generating training datasets for AI/ML guided therapeutic design.

Responsibilities:

• Develop and perform plate-based methodologies to address biotherapeutic polyreactivity for a range of modalities including antibodies, bi-/multi-specific antibodies, Fc-fusion, VHH, ADCs, etc.
• Serve as the lead and point of contact on antibody developability, managing requests, performing diverse assays, analyzing, communicating results, and cataloging of all data in databases.
• Execute on early to late-stage characterization for the developability of biotherapeutics including biophysical and bioanalytical methods involving plate-based assays, chromatographic methods, stability and aggregation propensities, structural properties, etc. with the goal of feeding training sets for ML and utilizing the output for improved therapeutic design.
• Demonstrate significant expertise in biophysical and bioanalytical characterization of large molecules to address hydrophobicity, polyreactivity, polyspecificity, self/cross‑interaction, colloidal and conformational stability, aggregation propensity, chemical stability, half-life (PK) predictors, and ADC toxicology predictors.
• Proactively identify liabilities for antibody developability, manufacturability or pharmacokinetics and work with protein engineering teams to guide design and optimization using sequence and computational prediction tools.
• Serve as the point of contact on antibody polyspecificity, managing requests and communicating results.
• Collaborate with multiple project teams in all disease areas to advise on key metrics of antibody developability, polyreactivity, manufacturability, and stability.
• Collaborate with our late-stage manufacturability scientists to support characterization of forced degradation studies.
• Develop new and innovative approaches and methodologies to accelerate early developability/manufacturability testing through miniaturization, increasing throughput and automating assay and data capture.
• Collaborate with the automation engineers for the high-throughput scaling of established assays.
• Prepare and present data and updates to project and functional teams, official reports and SOPs for internal and external purposes, internal documents/reports for regulatory filings.
• Stay current on biophysical and biochemical technologies and relevant literature, recognize risks and propose contingency plans.
• Collaborate with multiple teams across the organization, to support and share methodologies, align on efforts, and harmonize experimentation.
• Manage lab/equipment organization and maintenance.

Basic Qualifications:

Bachelor’s Degree with 7+ years of academic / industry experience

Or

Master’s Degree with 5+ years of academic / industry experience

Or

PhD with 2+ years of academic /industry experience

Preferred Qualifications:

• PhD in Biophysics, Biochemistry or related discipline with 2 years of relevant experience or MS with at least 5 years of work experience. Work experience is ideally in a biotech/pharma/industry environment.
• Proven track record and hands-on experience with biotherapeutic modalities and modern developability/manufacturability assays, methods and workflows.
• Expertise in high throughput plate-based assays including, but not limited to, ELISA, fluorescence, FLISA, HTRF, Flow cytometric, AlphaELISA, etc.
• Extensive experience in analytical liquid chromatograph (HIC, AnSEC, FcRn, Heparin Sulfate, RP, SMAC etc.).
• Demonstrated experience in antibody colloidal stability/self-interaction analysis (e.g. SI-BLI, AC-SINS, kD, viscosity, etc.).
• Experience in antibody conformational/thermal stability (e.g., Tm/Tagg, DSF, DSC, etc.).
• Experience in light scattering methodologies for analysis of biologic modalities and accelerated stability (DLS, SLS, SEC-MALS, Mass Photometry, etc.).
• Experience in biotherapeutic aggregation, solubility, and clipping analysis (AnSEC, Mass Photometry, PEG, CE-SDS, etc.).
• Deep understanding of antibody polyreactivity, stability, solubility, aggregation potential, chemical and other manufacturing liabilities, immunogenicity.
• Advanced knowledge of high throughput developability and pharmacokinetics including assessment and mitigation strategies.
• Familiarity with biotherapeutic manufacturability/accelerated stability testing methods including forced degradation, oxidation, isomerization, deamidation, etc.
• Prior experience with antibody biophysical characterization and binding assays of complex biologics (SPR, BLI, ITC, MST, etc.).
• Deep knowledge in antibody sequence, sequence motifs, and sequence liabilities.
• Broad familiarity with sequence- and structure-based protein modeling tools.
• Experience with high-throughput screening and automated liquid handling.
• Experience with large data generation, analysis and capture (e.g., LIMS systems).
• Exceptional organizational & time management skills, and attention to detail.
• Strong written and oral communication skills are essential.

Skills/Knowledge in one or more of the following areas are a plus:

• In silico modeling and prediction: homology modeling (e.g., MOE, Schrodinger, etc.), correlation of structure-based calculations/properties with experimental data, structure-activity relationship, etc.
• Knowledge/experience in protein and antibody engineering, structure, and design. Collaborate with the protein engineering teams to aid in the design of molecules with improved properties.
• Knowledge of antibody-based and computational databases for analysis and design of sequences (e.g., IMGT, OAS, AlphaFold2, etc.).
• Experience in aspects of structural biology (x-ray crystallography, cyro-EM, nsEM, NMR).
• Experience with programming languages like python, R, etc. is a plus.

For California Sites -  The starting compensation for this job is a range from $109,000 – $150,700, plus incentive cash and stock opportunities (based on eligibility). The starting pay takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation is decided based on demonstrated experience. For more on benefits, please visit our BMS Careers site. Eligibility for specific benefits listed in our careers site may vary based on the job and location.

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

When you join BMS, you are joining a diverse, high-achieving team united by a common mission. 

The Discovery Biotherapeutics team at BMS seeks to understand the structure and function of complex molecules such as bispecific antibodies, antibody drug conjugates and endogenous proteins in order to optimize their utility as therapeutic agents.  We collaborate with biology and translational scientists imbedded in the Thematic Research Centers in order to prosecute Targets and Biological pathways with disease modifying potential. By using a blend of internal and external technologies and capabilities, we work to discover and deliver first-in-class as well as best-in-class molecules that warrant clinical evaluation for patient benefit.

Here, you’ll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You’ll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.

Bristol Myers Squibb is seeking a highly motivated and innovative Scientist with demonstrated expertise in protein production to join our Discovery Biotherapeutics team. The successful candidate will be in the antigen technologies group and will collaborate closely with scientists in discovery biotherapeutics, biology, and other related groups. The candidate will be responsible for the recombinant protein production, including the design, expression, purification, and characterization. These proteins will be used in the binder discovery process and applied in biophysical experiment and structural biology to support BMS biotherapeutics programs.

Responsibilities:  

• Lead the antigen protein production by conducting recombinant protein construct design, expression, and purification at a milligram scale for early discovery research purposes.
• Analyze and characterize the protein quality to ensure sample quality meets the requirements for intended experiments.
• Optimize and troubleshoot expression and purification processes for challenging protein production.
• Conduct the membrane production at a milligram scale in detergent or detergent-free forms (amphipol, nanodisc), starting from the construct design, screen, expression test, to the large-scale productions, to support the binder discovery workflow and biophysical experiments.
• Manage lab equipment organization and maintenance.
• Serve as the point of contact on protein properties, manage the production requests, and communicate results.
• Collaborate with multiple project team members in discovery biotherapeutics and biology.
• Ensure proper planning and execution of experiments, adhering to timelines and project objectives.
• Accomplish goals under project team time lines.

Basic Qualifications:  

• BS degree with 7+ years of industry experience or MS degree with 5+ years of industry experience or PhD with 2 year academic/industry experience with Biochemistry, Biophysics, or similar field. 

Preferred Qualifications:

• Deep knowledge and experience of protein biochemistry and structural biology.
• PhD and 2+ years of relevant experience
• Extensive experience in mammalian culture (HEK293, CHO) for recombinant protein expression.
• Extensive experience in recombinant protein purification using various techniques such as affinity, ion exchange, and size exclusion chromatography at a milligram scale using AKTA Avant.
• Experience in protein analytical characterization including SDS-PAGE/CE-SDS, endotoxin, analytical SEC, SEC-MALS, Mass photometry, LC/MS, etc
• Experience in membrane protein production such as GPCR, transporter, and receptor is plus.
• Knowledge and experience in structural biology such as X-ray crystallography and cryoEM and computational modeling (AlphaFold2, etc) is a plus.
• Experience in antibody production for in vitro or in vivo usages is a plus.
• Knowledge and experience with CROs for custom protein production is a plus.
• Demonstrate excellent written and oral communication skills.
• Excellent time management and organizational skills.
• Ability to work in a multidisciplinary biologics discovery team.

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

When you join BMS, you are joining a diverse, high-achieving team united by a common mission. 

The Discovery Biotherapeutics team at BMS seeks to understand the structure and function of complex molecules such as bispecific antibodies, antibody drug conjugates and endogenous proteins in order to optimize their utility as therapeutic agents.  We collaborate with biology and translational scientists imbedded in the Thematic Research Centers in order to prosecute Targets and Biological pathways with disease modifying potential. By using a blend of internal and external technologies and capabilities, we work to discover and deliver first-in-class as well as best-in-class molecules that warrant clinical evaluation for patient benefit.

Here, you’ll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You’ll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.

The Functional Assays team within Discovery Biotherapeutics plays a key role in characterizing molecules to enable the discovery of first in class and/or best in class biotherapeutics. The Scientist position is in Cambridge, MA, working with cross-functional matrixed teams across other BMS sites. The position entails the utilization of broad in vitro biochemical and cellular techniques to accelerate primary antibody screen workflow execution and downstream mechanistic characterization of a wide range of biotherapeutic drug candidates, including antibody drug conjugates, bispecific and multi-specific antibodies, and other formats. Expertise in designing and executing validating primary screening assays and downstream functional assays for hit selection and characterization of leads will be vital too the discovery of efficacious biologics candidates build a full characterization of lead biologic candidates. The successful candidate is expected to be self-motivated, energetic, and detail oriented. The candidate should be able to thrive in a highly dynamic, supportive, yet independently thinking culture.

Key Responsibilities

• Develop fit-for-purpose primary screening assays and provide characterization support for lead molecules
• Explore commercial sources or design and execute cellular assays for functional characterization including signaling, internalization, and cytotoxicity readouts
• Characterize protein reagents using techniques including flow cytometry, biolayer interferometry, and homogeneous biochemical assays 
• Serve as functional assay representative on matrixed multidisciplinary project teams
• Analyze and present data to stakeholders
• Document experiments meticulously in Electronic Notebook

Basic Qualifications:

Bachelor’s Degree with 5+ years of academic or industry experience

Or

Master’s Degree with 3+ years of academic or industry experience

Or

PhD and no years of experience

Preferred Qualifications

• In-depth knowledge and hands-on experience in various techniques for protein and antibody characterization
• Experience with developing engineered cell lines for binding and functional screening assays
• PhD in a relevant discipline
• Experience with lentiviral transduction/CRISPR
• Experience with cell culture
• Experience with flow cytometry, or cell  imaging and other cellular assay techniques
• Proficiency in programming skills to enable automation processes such as high-throughput liquid handling
• Proficiency with database management/entry (such as Genedata or LIMS)Experience with cell culture
• Proficiency with data visualization using Spotfire
• Proficiency with DOE and JMP

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

Working with Us 
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible. 

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us  

 
Position Summary 

The Senior Engineer, Information Technology (IT) Manufacturing - Automation reports to the Manager of IT Automation and provides engineering (design and build) and technical support for laboratory and manufacturing systems to ensure efficient and compliant operation. They are responsible for acting as a technical resource to the engineering, manufacturing, maintenance, IT, and validation departments. This position will be responsible for incident resolution, database support, local network and infrastructure, controls systems specification, programming, simulation and testing, troubleshooting, repairs, start-up assistance, and project documentation as required.  

Key Responsibilities 

Support for new system deployments.  

• Completes deliverables during the design, delivery, commissioning of good manufacturing practices (GMP) computerized systems at the Phoenix site. 
• Provides support to project teams related to IT Digital Capability department requirements including user support models and data management. 
• Supports generation of validation and support documents (standard operating procedures (SOPs), Configuration Specification, etc.). 
• Executes protocols and/or test scripts for systems as required. 

Routine support for GMP computerized systems at the Phoenix Site 

• Performs routine user and system maintenance and advanced troubleshooting of automation and GMP computerized systems. 
• Identifies process improvements for existing automation and GMP computerized systems and works with management to initiate related projects to implement the improvement. 
• Initiates change controls and document changes/creation as necessary. 
• Provides advanced training to system end users. 
• Ensures systems are available for production use and any down time is minimized to reduce impact to user teams. 
• Requests quotes from vendors for approved equipment, software, and services. 
• Interacts with end users, IT, maintenance, and other support groups while troubleshooting issues. 

• Programmable Logic Controller (PLC) logic and programming with Allen Bradley PLCs, Human Machine Interface (HMI) and/or Supervisory control and data acquisition (SCADA) programming with Wonderware, Rockwell Automation, or Intellution software packages. 
• Ensure individual compliance with the health authority regulations and applicable department programs, including training, policies, and standard operating procedures. 
• Ensure the qualified state of all equipment, systems, and facilities are maintained according to site policies and procedures, and applicable regulatory requirements. 
• Acts as representative for IT Digital Capability department during interdepartmental projects. 
• Supports global projects that require support from IT Automation. 
• Perform other tasks as assigned. 

Travel requirements: 

• Requires travel < 10% of time. 

Qualifications & Experience 

• Advanced knowledge of MS office applications. 
• Intermediate knowledge of Windows operating systems and laboratory specific applications. 
• Intermediate knowledge of IT fundamentals including networking, virtual server technology, backup and recovery, security, active directory, and disaster recovery strategies. 
• Intermediate knowledge of coding and scripting, including PLC code and control software, including structured text on multiple platforms. 
• Advanced knowledge of IT system support. 
• Intermediate knowledge of Software Design Life Cycle. 
• Advanced knowledge of software support. 
• Intermediate knowledge of current good manufacturing practices (cGMP), GMP, Good Automated Manufacturing Practice (GAMP). 
• Advanced written and verbal communication skills. 
• Advanced organizational and time management skills. 
• Advanced critical reasoning and decision-making skills. 

• Advanced teamwork and facilitation skills. 
• Ability to develop others, delegate and motivate. 
• Requires strategic thinking and ability to work independently. 
• Ability to interpret / write general business documents. 
• Ability to interpret / write complex technical documents. 
• Requires excellent listening skills. 
• Qualitative training skills: responsiveness, enthusiasm, humor, sincerity, honesty, and tolerance. 
• Strong presentation development and delivery skills. 
• Ability to solve complex problems. 
• Ability to pass initial physical and annual monitoring. 
• Intermediate knowledge of mechanical, utility, and plant systems and the ability to troubleshoot automation used throughout the plant. 
• Ability to read electrical schematics, ladder logic, and piping and instrumentation diagram (P&ID) drawings as well as construction drawings. 
• Exceptional teamwork, organizational, and time management skills with the flexibility and ability to multi-task.  
• Ability to read electrical schematics, ladder logic, and P&ID drawings. 

Education and Experience: 

• Bachelor’s degree preferred, in Computer Science, Engineering, or related applied science. 
• 5 years’ relevant work experience required, preferably in a pharmaceutical or engineering environment.  
• An equivalent combination of education, experience, and training may substitute. 

Working Conditions: 

• The incumbent may be required to climb ladders or walk on catwalks at elevations above the floor. 
• The incumbent may be exposed to areas where noise levels are elevated. May require hearing protection during these times. 
• The incumbent may be required to walk outside for short periods of time. 
• The incumbent may be exposed to conditions that require safety glasses and hairnets.  
• The incumbent may be required to work at elevated heights, including walking on the roof. 
• The incumbent may be exposed to noise, gases, odors, and wet/slippery conditions. 
• Must be able to work at least 8 hours per day or longer during shutdown periods. 
• Requires the ability to concentrate during lengthy technical discussions.  
• The incumbent will be required to work in an office environment potentially requiring ergonomic considerations. 
• The incumbent will be required to work in a conference room environment for moderate periods of time. 
• The incumbent will be required to work with computers for up to 8 hours per day, including typing and viewing computer screens during this time. 
• Occasional excursions to labs, production area, or warehouse requiring some level of gowning. 

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

When you join BMS, you are joining a diverse, high-achieving team united by a common mission. 

The Discovery Biotherapeutics team at BMS seeks to understand the structure and function of complex molecules such as bispecific antibodies, antibody drug conjugates and endogenous proteins in order to optimize their utility as therapeutic agents.  We collaborate with biology and translational scientists imbedded in the Thematic Research Centers in order to prosecute Targets and Biological pathways with disease modifying potential. By using a blend of internal and external technologies and capabilities, we work to discover and deliver first-in-class as well as best-in-class molecules that warrant clinical evaluation for patient benefit.

Here, you’ll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You’ll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.

As part of the Discovery Biotherapeutics efforts at BMS, the Principal Scientist will play a key role in advancing antibody drug conjugates technologies at BMS. 

We are looking for an experienced, collaborative, highly motivated scientist and leader with deep expertise in antibody drug conjugates (ADC) technologies. The candidate should have deep understanding and experience antibody drug conjugation technologies. The candidate is expected to have strong collaborative skills to ensure robust partnerships with biologists, antibody discovery and engineering & bioanalytical scientists to advance ADC projects.

A prove track record of hands-on experience with antibody-drug conjugation chemistry, analytical characterization and developability of ADCs is a must have for this position.

Responsibilities:

• The role will involve leading and carrying out laboratory experiments related to ADC conjugation, associated purification and analytical characterization of the conjugates
• Design, produce, and characterize antibody-drug conjugates (ADCs) with a high degree of independence
• Proactively advise and share knowledge and expert opinions with bench scientists, peers and senior management. Mentor staff in troubleshooting strategic and experimental issues
• Record of leading project teams through different stages of pre-clinical discovery
• Ensure highest standard of quality in antibody-conjugate productions in alignment with product development guidelines and QC criteria
• Collaborate with a diverse team of biologists and chemists to answer scientific questions and drive forward new conjugation platforms
• Leverage knowledge of bioconjugation and protein engineering to develop new therapeutic ADC technologies.
• The candidate will encourage ideas for continuous improvement activities & new technology development and initiative within work group.
• Contribute to patents, publications, and technical reports.

Basic Qualifications:

Bachelor’s Degree with 8+ years of academic or industry experience

Or

Master’s Degree with 6+ years of academic or industry experience

Or

PhD with 4+ years of academic or industry experience

Preferred Qualifications:

A PhD with 4+ years of  industry experience

Extensive hands-on experience with therapeutic antibody and ADC discovery

Deep knowledge of bioconjugation chemistries (lysine, inter-chain cysteine and/or site-specific cysteine and other) is needed.

Experience in development of purification strategies using various chromatographic techniques such as affinity, size exclusion, ion-exchange, hydrophobic interaction, and tangential flow filtration (TFF)

Experience in analytical characterization of ADCs including SEC, RP-HPLC, LC-MS, CE-SDS, ELISA, DSC, and HIC

Experience with biological assays such as measuring cytotoxic activity for ADC characterization.

Hands-on experience with siRNA/ASO conjugations and analytics is a plus.

Demonstrated record of scientific accomplishments and publications.

Excellent written and oral communication skills and ability to interpret results and contribute to multidisciplinary biologics discovery teams

For California Sites -  The starting compensation for this job is a range from $121,000 – $167,200, plus incentive cash and stock opportunities (based on eligibility). The starting pay takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation is decided based on demonstrated experience. For more on benefits, please visit our BMS Careers site. Eligibility for specific benefits listed in our careers site may vary based on the job and location.

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

At Bristol Myers Squibb we are reimagining the future of cell therapy. With our bold ambition, backed by a best-in-the-industry team and long-term commitment, we are leading the way to unlock the full promise of cell therapy as we strive to put more patients on the path to a cure. If you are ready to challenge yourself, accelerate your career, and give new hope to patients, there’s no better place than here at BMS with our Cell Therapy team.

The Senior Manager, CTO Capital Projects will develop, implement, and oversee capital projects to support Cell Therapy Operations (CTO) at the Summit West Site.  This role will be focused on managing capital projects ($5M+) responsible for interfacing cross-functionally with both internal groups, external clients and stakeholders to ensure projects are delivered on time and within budget.  This position will utilize their breadth of knowledge across facilities and engineering to drive CTO business growth strategies across the Summit West Site and ensure adherence to regulatory compliance and effective project execution. 

Shifts Available:

M-F, standard working hours

Responsibilities:

• Lead the development of the Capital Project scope and Master Planning initiatives in support of the business strategy alignment with CTO clients and stakeholders.
• Exhibit project leadership and effective decision-making throughout each project.
• Lead and promote effective teamwork by engaging Facilities, ECQ & EHS, as well as key clients and stakeholders.
• Lead the scheduling, planning, control, and effective coordination of all the parallel activities related to each project and maintain project schedule through unanticipated schedule challenges.
• Coordinate with Procurement and Project Team in generating RFP documents for engineering deliverables typically for Equipment Purchases, Design, Construction & Qualification efforts.
• Manage A/E Firms through the BMS Stagegate Process to effectively deliver on meeting end user functional/design requirements and overall project goals.
• Manage and coordinate with Construction Managers (CMs) from estimating, pre-construction, demolition, construction and commissioning in alignment with design & functional requirements.
• Ensure all work complies with BMS Site Safety Requirements and ensure all involved individuals are in compliance with required trainings.
• Utilize broad knowledge of the functional requirements of the pharmaceutical facilities and engineering best practices to ensure that appropriate internal and external resources are incorporated into the project design and execution.
• Achieve a cost-effective, functional outcome with the use of design guidelines and standards, value engineering, life cycle costing and engineering best practices.
• Assure that the construction project and the finished facility are compliant with all applicable safety, regulatory, legal requirements.
• Achieve effective financial control through management of project scope, estimating, effective use of SAP, RPM, budget control tools, risk management, and project closeout.
• Achieve high customer satisfaction by delivering finished projects that are fully commissioned, qualified, and ready for startup/occupancy and meets all requirements of stakeholders and stays within a predetermined schedule.
• Participate and lead shutdown planning & coordination for effective and timely execution of Capital Project related activities with minimal disruption to Manufacturing.

Knowledge & Skills:

Basic Requirements:

• Experience managing GMP related EPCMV projects ($5M+) within a Cell/Gene Therapy or Pharmaceutical Manufacturing Environment is required.
• Bachelor’s Degree with 10+ years of relevant work experience demonstrating leadership capabilities, or an equivalent combination of education and experience may be considered:  Bachelor’s degree in Chemical or Mechanical Engineering preferred, EIT/PE License and plus
• Demonstrated success leading multi-disciplinary and multi-functional teams and demonstrated strength in stakeholder management, especially integration of design, construction, and qualification firms
• Interpersonal / facilitation skills necessary to interface and influence all levels of management
• Significantly demonstrated Project Management expertise for design, construction, qualification, and start-up involving all areas of Pharmaceutical Manufacturing, Pilot Plants, QC Laboratories and Warehousing
• Strong terminology of construction terminology and legal content of construction contracts and documents.
• Experience with supervising construction contractors especially in review/approval of Pre-Task Plans (PTPs) and Job Hazard Analysis (JHA) documentation
• Experience with Process Hazard Analysis, (PHA), Process Safety Management (PSM) and Pre-Startup Safety Review (PSSR)
• Background in use of the Stage Gating Process within Capital Project Workflow
• Understanding of financial management as it relates to capital and expense spending and project cash flow forecasting
• Familiar with the use of RPM (Project Capital System) or equivalent and SAP (Purchase Order System)
• Demonstrated ability to be proactive in solving challenging project issues with the ability to develop creative solutions.
• Experience in total project delivery from concept to validation and startup process
• Proficient Experience with Building Management System, HVAC and Liquid Nitrogen / Cryo Systems, a plus
• Experience with initiating Change Controls, performing Impact Assessments, Change Actions and executing CAPAs as needed to complete assigned Engineering Department Scope of Work.

 
Working Conditions:

• Occasional stooping, bending, stretching, pushing, pulling, reaching and/or light lifting and pushing of moving carts may be required
• Ability to sit, stand, walk and move within workspace for extended periods

Environmental Contiditions:

• Environment may include working in office, or in a laboratory / manufacturing area
• Ability to work safely in an environment with hazardous, radioactive and infectious materials and waste
• Ability to work safely in an environment with exposure to high temperatures, / pressure steam, and other fluids, compressed gasses, odors, various noise levels, moving parts, vibration wet / slippery areas and high voltage energy supplies
• Environment may include working at heights, in cold temperatures, and or constricted spaces
• Ability to work safely when working along or working with others.

BMSCART

#LI-ONSITE

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

At Bristol Myers Squibb we are reimagining the future of cell therapy. With our bold ambition, backed by a best-in-the-industry team and long-term commitment, we are leading the way to unlock the full promise of cell therapy as we strive to put more patients on the path to a cure. If you are ready to challenge yourself, accelerate your career, and give new hope to patients, there’s no better place than here at BMS with our Cell Therapy team.

The Manager, CTO Plant Engineering will directly manage, develop, and drive efficient and reliable operation of manufacturing facilities and utilities across all Summit West Cell Therapy Operations.  This hands-on role will be focused on providing direction and support to the engineering and facilities teams for coordinating maintenance activities, troubleshooting, assessing adherence with BMS / regulatory standards, managing compliance initiatives (deviations/CAPAs), executing capital / expense projects (<$500K) & driving continuous improvement initiatives.  You will collaborate with cross-functional teams to help develop, implement, and manage projects to meet goals in terms of safety, quality, output, and cost with key focus on maximizing efficiencies for facility and utility systems.  This role will require management of direct reports, outside resources, and their own work load.

Shifts Available:

M-F, standard working hours

• Please note: there will be times where the hours and days will have to be flexible (early mornings / weekends)

Responsibilities:

• Manage maintenance technicians and outside service providers especially in performing routine and corrective work orders related to HEPA Filter Certifications, Air Balancing & Filter Integrity Testing (FIT), inclusive of supporting related deviations and CAPAs. 
• Provides Engineering Support required for supporting Mechanical, Electrical & Plumbing (MEP) manufacturing related utility systems inclusive of HVAC, Steam, Chilled Water, Compressed/Process/Breathing Air, Liquid Nitrogen, CO2, Electrical (Normal, UPS, Emergency Generator), etc.  Ensure compliance of utilities with GMPs, industry best practices, and BMS directives.  Support commissioning and validation activities for specified equipment.
• Coordinate projects and maintenance activities with operations to minimize Disruptions to Controlled Environments (DCE) for controlled and uncontrolled outages.  Create or contribute to quality plans that ensure orderly service interruptions and smooth return to service.  Take lead in troubleshooting systems and take proactive approach in limiting downtime.
• Actively lead HVAC and Building Automation System (BAS) troubleshooting events and effectively remediate.
• Seek out and apply novel engineering approaches to improve plant utility systems where possible to maximize reliability and efficiencies.  Act as lead Project Manager on Smaller Capital / Expense projects to identify user requirements and engage with A/E Firms and Construction Management Firms for execution.   Act as Assistant Project Manager in support of large Capital Projects.
• Coordinate all field work to ensure proper safety procedures are in place such as PreTask Plans (PTP), Job Hazard Analysis (JHA), Process Analysis (PHA), Pre-Startup Safety Reviews (PSSRs) to ensure the safe execution of projects or maintenance activities where required.  Ensure all work complies with BMS Site Safety Requirements and ensure all involved individuals have required trainings.
• Work with Operations & Quality Organizations to procure benchtop Capital Equipment and assess available space and utilities required in field.  Follow through for complete installation prepped for Commissioning and/or Qualification.
• Engage with Facilities, Maintenance, ECQ, Global Engineering, and external resources to engineer solutions of Deviations, CAPAs, Audit Findings, Safety findings, etc.... 
• Act as Engineering Lead to continuously access adherence with BMS and Regulatory standards against guidance documents.  Must be clearly able to identify & communicate gaps and work with Engineering team to remediate as needed. 
• Review, redline, approve, and update engineering drawings and other technical documentation to ensure that it remains current. 
• Initiate Facility and Engineering related Change Controls as required to obtain quality endorsement of proposed changes.
• Partner with facility and reliability engineers to investigate adverse trends and execute CAPAs as required.  Collaborate with other functions, such as Manufacturing Operations, Quality Assurance, Facilities, ECQ and EHS, for all inclusive approach in determining successful outcome. Identify continuous improvement, energy conservation, and cost savings opportunities.
• May serve as a site SME for critical utility systems and interact with regulatory authorities or internal auditors. Ensure inspection-readiness of key systems. Develop responses or action plans to correct any deficiencies.

Basic Requirements:

• Bachelor’s degree in mechanical engineering, chemical engineering, or a related field.
• Proven experience (5+ years) in a similar role within the pharmaceutical or related industry.
• In-depth knowledge of pharmaceutical manufacturing processes, equipment, and systems, including but not limited to HVAC, mechanical & electrical systems, cleanrooms, and process automation.
• Strong understanding of regulatory requirements, such as GMP, GDP, and OSHA guidelines.
• Previous experience in Facility Operations & Maintenance, Design, Construction and Qualification.
• Proficient in using computer-aided design (CAD) software and other engineering tools.
• Excellent problem-solving and analytical skills with the ability to identify and resolve complex technical issues.
• Effective communication and interpersonal skills to collaborate with cross-functional teams and external stakeholders.
• Detail-oriented with a strong commitment to quality, safety, and compliance.
• Ability to manage multiple projects simultaneously and prioritize tasks effectively

BMSCART

#LI-ONSITE

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.