Job Details

Senior Associate Scientist CV Discovery Biology

Drug Discovery Research

icon-location-marker Brisbane - CA - US
Posted 14 days ago Full_time R1583607

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

When you join BMS, you are joining a diverse, high-achieving team united by a common mission.

The Immunology and Cardiovascular Thematic Research Center (TRC) at BMS is one of the fundamental Research and Early Development (R&ED) units delivering therapeutics to patients. Our mission is to create transformative medicines of tomorrow based on the cutting-edge science of today. We leverage BMS’s internal invention of engine that includes industry-leading expertise in small molecule chemistry, protein biotherapeutics, cell therapy, protein degradation, nucleic acids, and other therapeutic modalities. We work closely our R&ED colleagues in clinical and non-clinical development, project leadership, translational medicine, and informatics to advance therapies based on a deep understand of causal human biology. Further, we collaborate across the biopharmaceutical ecosystem to establish partnerships that complement our internal expertise.

Here, you’ll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You’ll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.

Position Responsibilities

We are seeking an experienced, knowledgeable, and self-motivated scientist to join our CV Discovery Biology team to support drug discovery for sarcomeric and genetic cardiomyopathy programs within the BMS organization. The successful candidate will work collaboratively with teams in Molecular Biology, Sarcomere Biology, and Pharmacology to develop novel approaches to support target identification, HTS, and mechanism of action studies for BMS’s Cardiovascular Research and Early Discovery efforts.

Essential Duties and Job Responsibilities: 

  • Characterization of protein targets involved in cardiac diseases as well as determining the molecular mechanism of action of drug candidates.
  • Develop and implement novel biochemical/biophysical assays to support and grow BMS’s drug discovery efforts.
  • In vitro assay development and optimization, mechanism-of-action studies, developing experimental methods to assess protein-protein interactions, ligand-protein binding kinetics.
  • Presenting work at internal and external meetings and preparing data for team presentations.
  • The scientist will work in a multidisciplinary environment and is expected to collaborate effectively with other members. 

Experience

Basic Qualifications:

  • Master with 2+ years of academic/industry experience.

Or

  • Bachelor with 4+ years of academic/industry experience

Preferred Qualifications:

  • Experience in Sarcomere small molecule drug discovery with varieties of biochemical/biophysical/cell-based methods for Hits characterization and MOA study.
  • Broad experience in developing and optimizing biochemical/biophysical/cell-based assays (e.g. AlphaScreen, TR-FRET, luminescence, fluorescence polarization, MST, SPR, ITC, Hibit, CTG etc).
  • Experience of protein expression and purification using AKTA Chromatography.
  • Experience with enzyme kinetics and stopped-flow kinetics is preferred. 
  • Hands on liquid handler/automation is a plus.
  • Strong problem-solving skills, ability to develop new techniques and methodologies.  
  • Excellent organizational and time management skills.
  • Must be self-motivated, detail-oriented, collaborative, and able to work effectively in a multidisciplinary discovery team.

The starting compensation for this job is a range from $82,000 - $102,000 plus incentive cash and stock opportunities (based on eligibility).

 

The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed.

 

Final, individual compensation will be decided based on demonstrated experience.

 

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit our BMS Career Site.

 

Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown days between Christmas and New Year’s holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.