Job Details
Drug Discovery Research
Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.
Job Description
We are seeking an experienced individual to join the Protein Homeostasis-Cell Biology team within the Oncogenesis Thematic Research Center at Bristol Myers Squibb in San Diego, CA. We are looking for a highly collaborative, passionate, and motivated biologist with broad experience in molecular and cellular biology. The candidate will be part of a growing team focused on target validation, target biology support and developing novel assay platforms to drive protein degradation drug discovery efforts. The individual will be involved in executing biology bench studies that will advance the understanding of selected targets and their biological mechanisms of action, which will help generate the optimal screening funnel assays, enable compound triaging, and identify potential drug candidates. This position offers an exciting opportunity to work in a dynamic and innovative environment focused on novel protein homeostasis concepts and modalities.
Position Responsibilities
Engineer cell lines for desired targets using Lenti/CRISPR based strategies.
Maintain, passage, and cryopreserve parental and engineered cells lines.
Perform experiments to identify, validate and study target binders.
Plan and run assays to measure cell growth, apoptosis, cell cycle, and protein levels.
Experience in automation and screening a plus.
Collaborate with colleagues in other functional areas including proteomics, informatics, translational research, and chemistry to pursue target validation experiments and support drug discovery efforts.
Maintain accurate electronic laboratory notebooks in a timely fashion and prepare technical reports, summaries, protocols, etc.
Present data at internal scientific meetings.
Basic Qualifications:
Bachelor’s Degree
4+ years of academic and / or industry experience
Or
Master’s Degree
2+ years of academic and / or industry experience
Preferred Qualifications:
A self-motivated and creative scientist with a strong can-do attitude.
Excellent cellular and molecular biology knowledge/experience (plasmid design, generation of transient/stable cell lines using Lenti/CRISPR systems, IP/pull down assays, Western blot, PCR, FACS, cell cycle assays, flow cytometry).
Familiarity with automatic, robotic dispensers, liquid handlers.
Experience in functional assays such as viability and cell growth assays.
Works well in a collaborative environment, demonstrating adaptability and an ability to deliver time-sensitive studies.
Possesses strong interpersonal and communication skills and an eagerness to engage in a setting that thrives on rigorous science and innovative ideas.
Perform literature searches, read, and interpret papers to contribute to project development and troubleshoot experiments.
Willingness and ability to learn new methods and skills.
Familiar with Windows, MS Office, GraphPad PRISM, FlowJo; capable of analyzing and summarizing complex data.
Other relevant experience:
Experience with PPI techniques, e.g., RET, APEX/BioID
Small molecule drug development (hit discovery, hit validation, dose-response studies)
The starting compensation for this job is a range from $83,000 - $114,400 plus incentive cash and stock opportunities (based on eligibility).
The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed.
Final, individual compensation will be decided based on demonstrated experience.
Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit our BMS Career Site.
Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown days between Christmas and New Year’s holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.
#LI-Onsite
If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.
Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
On-site Protocol
BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:
Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.
BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.
BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.
BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.
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